Plaque formation by bluetongue virus.

نویسندگان

  • P G Howell
  • D W Verwoerd
  • R A Oellermann
چکیده

The cytopathic changes produced by bluetongue virus were first observed by Haig, McKercher & Alexander (1956) in monolayer roller tube cultures of primary lamb kidney ce ll s. Subsequently, Fernandes (1959) described the growth and cytopathic effects of a virulent as well as a homologous egg-adapted strain at the thirtysixth passage level, in cultures of human amnion (Fernandes), Chang liver, clonal Hela HB2, McCoy synovial , Henles intestine, bovine kidney, Chang conjunctiva and NCTC A2414 clonal human skin cells. By means of the fluorescent antibody staining technique, Livingstone & Moore (1962) concluded that multiplication of virus occurred within the cytoplasm of infected cells .

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عنوان ژورنال:
  • The Onderstepoort journal of veterinary research

دوره 34 2  شماره 

صفحات  -

تاریخ انتشار 1967